I have been looking forward to this for a long time: the publication of NTP / OHAT systematic review draft protocols for the association between BPA exposure and obesity, and PFOA/PFOS exposure and immunotoxicity.
I am particularly interested in how they propose managing the different streams of evidence from toxicological research (a major difference between evidence-based medicine, which focuses on clinical trials, toxicological data is much more heterogeneous, with epidemiological, animal and test-tube research all needing to be factored in).
Their proposals for risk-of-bias analysis, a key component of EBM, will also make very interesting reading. NTP will be hosting a web-based informational meeting on 23 April to explain what they are doing (details below)
From the NTP/OHAT Website
- Download the Draft OHAT Approach for Systematic Review and Evidence Integration for Literature-Based Health Assessments – February 2013
- Draft Protocol for Systematic Review to Evaluate the Evidence for an Association Between Bisphenol A (BPA) Exposure and Obesity
- Draft Protocol for Systematic Review to Evaluate the Evidence for an Association Between Perfluorooctanoic Acid (PFOA) or Perflurooctane Sulfonate (PFOS) Exposure and Immunotoxicity
Web-Based Informational Meeting (April 23, 12-4:00 PM EDT)
The NTP will hold a public, web-based, informational meeting on April 23, 2013, 12:00-4:00p.m. Eastern Daylight Time to provide an overview of the Draft OHAT Approach – February 2013, describe the contents in the two case-study protocols, and respond to questions from the public on any of the documents. The deadline to register for the informational meeting is April 16, 2013. The meeting may end earlier depending on the number of registered participants and will be cancelled if there are no registered participants by close of business on April 16, 2013. Registrants will receive information by email to access the web-based meeting on or before April 19, 2013.